Trials & Projects

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Clinical Trials & Projects

ECOPOP brings together a portfolio of clinical trials and research initiatives focused on improving outcomes in early colorectal cancer.

Our projects evaluate innovative, less invasive treatment strategies while maintaining oncological safety, with a strong emphasis on patient quality of life, long-term outcomes and more individualized treatment decisions.

Active Trials

ETHOS Trial

Recruiting

A randomized controlled trial comparing endoscopic full-thickness resection with standard surgical resection in early-stage colon cancer.

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SCAR Trial

Recruiting

A randomized trial evaluating whether eFTR can safely replace surgery after incomplete endoscopic removal of early colon cancer.

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T-REX Trial

Preparation

A randomized trial comparing active surveillance with adjuvant chemoradiotherapy after local excision of intermediate-risk T1 rectal cancer.

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Research Projects

What connects the ECOPOP portfolio?

Reducing overtreatment

ECOPOP asks when major treatment can be safely avoided without compromising cancer outcomes.

Organ preservation

The trials focus on strategies that may help preserve bowel and rectal function whenever clinically appropriate.

Evidence before implementation

New approaches are tested in randomized trials before being considered for broader clinical use.

Shared decision-making

ECOPOP aims to support more individualized treatment decisions for patients and clinical teams.

Interested in ECOPOP?

Patients, clinicians and clinical centres can find dedicated information about ECOPOP trials, participation and collaboration opportunities.

Trials Overview

ECOPOP coordinates multiple clinical trials across international centres, focusing on organ-preserving treatment strategies.

Status: ongoing & upcoming
Focus: early colorectal cancer

Participation

Centres interested in joining ongoing trials or patients seeking participation can contact the coordination team.

Email:
ecopop@gumed.edu.pl